BDBM50395475 CHEMBL2163350

SMILES: CCC(C(=O)Nc1ccccc1-n1cccc1)c1ccccc1

InChI Key: InChIKey=YMKSNPNHFDHINA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50395475 (CHEMBL2163350) Show SMILES CCC(C(=O)Nc1ccccc1-n1cccc1)c1ccccc1 Show InChI InChI=1S/C20H20N2O/c1-2-17(16-10-4-3-5-11-16)20(23)21-18-12-6-7-13-19(18)22-14-8-9-15-22/h3-15,17H,2H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay				J Med Chem 55: 6975-9 (2012) Article DOI: 10.1021/jm300700v BindingDB Entry DOI: 10.7270/Q2KD2017
					More data for this Ligand-Target Pair