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BDBM50395482 CHEMBL2163665

SMILES: CCC(C(=O)Nc1cccc(c1)N1CCCC1)c1ccccc1

InChI Key: InChIKey=IYXGTCQIDUPPCC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395482   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
KCNQ (Kv7) potassium channel


(Homo sapiens (Human))
BDBM50395482
PNG
(CHEMBL2163665)
Show SMILES CCC(C(=O)Nc1cccc(c1)N1CCCC1)c1ccccc1
Show InChI InChI=1S/C20H24N2O/c1-2-19(16-9-4-3-5-10-16)20(23)21-17-11-8-12-18(15-17)22-13-6-7-14-22/h3-5,8-12,15,19H,2,6-7,13-14H2,1H3,(H,21,23)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay


J Med Chem 55: 6975-9 (2012)


Article DOI: 10.1021/jm300700v
More data for this
Ligand-Target Pair