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BDBM50395511 CHEMBL2164058

SMILES: O=C(Nc1ccccc1N1CCCC1)C1CCOc2ccccc12

InChI Key: InChIKey=ZXIFWITXVQJGGJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395511   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
KCNQ (Kv7) potassium channel


(Homo sapiens (Human))
BDBM50395511
PNG
(CHEMBL2164058)
Show SMILES O=C(Nc1ccccc1N1CCCC1)C1CCOc2ccccc12
Show InChI InChI=1S/C20H22N2O2/c23-20(16-11-14-24-19-10-4-1-7-15(16)19)21-17-8-2-3-9-18(17)22-12-5-6-13-22/h1-4,7-10,16H,5-6,11-14H2,(H,21,23)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay


J Med Chem 55: 6975-9 (2012)


Article DOI: 10.1021/jm300700v
More data for this
Ligand-Target Pair