BDBM50395516 CHEMBL2164053

SMILES: CC(C)CC(C(=O)Nc1ccccc1N1CCCC1)c1ccccc1

InChI Key: InChIKey=DLHMPCIOGCSHER-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KCNQ (Kv7) potassium channel (Homo sapiens (Human))	BDBM50395516 (CHEMBL2164053) Show SMILES CC(C)CC(C(=O)Nc1ccccc1N1CCCC1)c1ccccc1 Show InChI InChI=1S/C22H28N2O/c1-17(2)16-19(18-10-4-3-5-11-18)22(25)23-20-12-6-7-13-21(20)24-14-8-9-15-24/h3-7,10-13,17,19H,8-9,14-16H2,1-2H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay				J Med Chem 55: 6975-9 (2012) Article DOI: 10.1021/jm300700v BindingDB Entry DOI: 10.7270/Q2KD2017
					More data for this Ligand-Target Pair