BDBM50395730 CHEMBL2164450
SMILES: Nc1ncc(CC(C[Se][Se]CC(Cc2cnc(N)c(Cl)c2)C(O)=O)C(O)=O)cc1Cl
InChI Key: InChIKey=LKLRNWHRLUKWFJ-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carboxypeptidase B (Sus scrofa) | BDBM50395730 (CHEMBL2164450) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Showa Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of pig pancreatic carboxypeptidase B using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins b... | J Med Chem 55: 7696-705 (2012) Article DOI: 10.1021/jm300735t BindingDB Entry DOI: 10.7270/Q2N58NHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxypeptidase B (Sus scrofa) | BDBM50395730 (CHEMBL2164450) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Showa Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of pig pancreatic carboxypeptidase B using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins b... | J Med Chem 55: 7696-705 (2012) Article DOI: 10.1021/jm300735t BindingDB Entry DOI: 10.7270/Q2N58NHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxypeptidase B2 isoform A (Homo sapiens (Human)) | BDBM50395730 (CHEMBL2164450) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Showa Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human activated TAFI using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by spectrophot... | J Med Chem 55: 7696-705 (2012) Article DOI: 10.1021/jm300735t BindingDB Entry DOI: 10.7270/Q2N58NHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxypeptidase B2 isoform A (Homo sapiens (Human)) | BDBM50395730 (CHEMBL2164450) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Showa Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human activated TAFI using Hip-Arg as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by spectrophot... | J Med Chem 55: 7696-705 (2012) Article DOI: 10.1021/jm300735t BindingDB Entry DOI: 10.7270/Q2N58NHV | |||||||||||
More data for this Ligand-Target Pair |