BDBM50395744 CHEMBL2164831

SMILES: CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)cc(Cl)c23)c2ccc(Cl)cc2)CC1

InChI Key: InChIKey=QWXCJLADFZSOQG-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395744 (CHEMBL2164831) Show SMILES CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)cc(Cl)c23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C21H21Cl3N4O2/c1-27-6-8-28(9-7-27)12-18(29)26-21(13-2-4-14(22)5-3-13)19-16(24)10-15(23)11-17(19)25-20(21)30/h2-5,10-11H,6-9,12H2,1H3,(H,25,30)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Displacement of [125I]-ghrelin from human GHSR1 expressed in CHO-CREluc cells after 1 hr by scintillation counting				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50395744 (CHEMBL2164831) Show SMILES CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)cc(Cl)c23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C21H21Cl3N4O2/c1-27-6-8-28(9-7-27)12-18(29)26-21(13-2-4-14(22)5-3-13)19-16(24)10-15(23)11-17(19)25-20(21)30/h2-5,10-11H,6-9,12H2,1H3,(H,25,30)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assay				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair