Found 2 hits for monomerid = 50395810 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50395810
(CHEMBL2165183)Show SMILES CC(O)CN(Cc1cccc2ccccc12)c1cc(nc(=O)[nH]1)N1CCOCC1 Show InChI InChI=1S/C22H26N4O3/c1-16(27)14-26(15-18-7-4-6-17-5-2-3-8-19(17)18)21-13-20(23-22(28)24-21)25-9-11-29-12-10-25/h2-8,13,16,27H,9-12,14-15H2,1H3,(H,23,24,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus infected cells using DiC8-PI(4,5)P2 as substrate after 20 mins by ... |
Bioorg Med Chem Lett 22: 6671-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.102
BindingDB Entry DOI: 10.7270/Q2445NKM |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50395810
(CHEMBL2165183)Show SMILES CC(O)CN(Cc1cccc2ccccc12)c1cc(nc(=O)[nH]1)N1CCOCC1 Show InChI InChI=1S/C22H26N4O3/c1-16(27)14-26(15-18-7-4-6-17-5-2-3-8-19(17)18)21-13-20(23-22(28)24-21)25-9-11-29-12-10-25/h2-8,13,16,27H,9-12,14-15H2,1H3,(H,23,24,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus infected cells using DiC8-PI(4,5)P2 as substrate after 20 mins by... |
Bioorg Med Chem Lett 22: 6671-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.102
BindingDB Entry DOI: 10.7270/Q2445NKM |
More data for this
Ligand-Target Pair | |
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