null

SMILES: OCCN(Cc1cccc2ccccc12)c1cc(nc(=O)[nH]1)N1CCOCC1

InChI Key: InChIKey=VHHVRHAXPGTSLF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395813   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50395813 (CHEMBL2165180) Show SMILES OCCN(Cc1cccc2ccccc12)c1cc(nc(=O)[nH]1)N1CCOCC1 Show InChI InChI=1S/C21H24N4O3/c26-11-8-25(15-17-6-3-5-16-4-1-2-7-18(16)17)20-14-19(22-21(27)23-20)24-9-12-28-13-10-24/h1-7,14,26H,8-13,15H2,(H,22,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus infected cells using DiC8-PI(4,5)P2 as substrate after 20 mins by ...				Bioorg Med Chem Lett 22: 6671-6 (2012) Article DOI: 10.1016/j.bmcl.2012.08.102 BindingDB Entry DOI: 10.7270/Q2445NKM
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50395813 (CHEMBL2165180) Show SMILES OCCN(Cc1cccc2ccccc12)c1cc(nc(=O)[nH]1)N1CCOCC1 Show InChI InChI=1S/C21H24N4O3/c26-11-8-25(15-17-6-3-5-16-4-1-2-7-18(16)17)20-14-19(22-21(27)23-20)24-9-12-28-13-10-24/h1-7,14,26H,8-13,15H2,(H,22,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus infected cells using DiC8-PI(4,5)P2 as substrate after 20 mins by...				Bioorg Med Chem Lett 22: 6671-6 (2012) Article DOI: 10.1016/j.bmcl.2012.08.102 BindingDB Entry DOI: 10.7270/Q2445NKM
					More data for this Ligand-Target Pair