BDBM50396187 CHEMBL2172056

SMILES: OC(=O)c1n[nH]c(CCc2ccccc2)c1Cc1cccc(c1)-c1ccc(F)cc1

InChI Key: InChIKey=PPGFJRINCMDGKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxyacid oxidase 2 (Rattus norvegicus)	BDBM50396187 (CHEMBL2172056) Show SMILES OC(=O)c1n[nH]c(CCc2ccccc2)c1Cc1cccc(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H21FN2O2/c26-21-12-10-19(11-13-21)20-8-4-7-18(15-20)16-22-23(27-28-24(22)25(29)30)14-9-17-5-2-1-3-6-17/h1-8,10-13,15H,9,14,16H2,(H,27,28)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Advinus Therapeutics Curated by ChEMBL					Assay Description Inhibition of rat Hao2-mediated oxidation of 2-hydroxyoctanoic acid assessed as proportionate release of H2O2				Bioorg Med Chem Lett 22: 4341-7 (2012) Article DOI: 10.1016/j.bmcl.2012.05.020 BindingDB Entry DOI: 10.7270/Q20866FZ
					More data for this Ligand-Target Pair