BDBM50396771 CHEMBL2172383

SMILES: OC[C@H]1O[C@]2(OCc3ccc(Cc4ccc(cc4)C(F)(F)F)cc23)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=IBYQFLWODSDFFV-OBKDMQGPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50396771 (CHEMBL2172383) Show SMILES OC[C@H]1O[C@]2(OCc3ccc(Cc4ccc(cc4)C(F)(F)F)cc23)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C21H21F3O6/c22-21(23,24)14-5-2-11(3-6-14)7-12-1-4-13-10-29-20(15(13)8-12)19(28)18(27)17(26)16(9-25)30-20/h1-6,8,16-19,25-28H,7,9-10H2/t16-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.2	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 mins				J Med Chem 55: 7828-40 (2012) Article DOI: 10.1021/jm300884k BindingDB Entry DOI: 10.7270/Q2MW2J9K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50396771 (CHEMBL2172383) Show SMILES OC[C@H]1O[C@]2(OCc3ccc(Cc4ccc(cc4)C(F)(F)F)cc23)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C21H21F3O6/c22-21(23,24)14-5-2-11(3-6-14)7-12-1-4-13-10-29-20(15(13)8-12)19(28)18(27)17(26)16(9-25)30-20/h1-6,8,16-19,25-28H,7,9-10H2/t16-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent [14C]methyl-alpha-D-glucopyranoside uptake after 45 mins				J Med Chem 55: 7828-40 (2012) Article DOI: 10.1021/jm300884k BindingDB Entry DOI: 10.7270/Q2MW2J9K
					More data for this Ligand-Target Pair