null

SMILES: Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4OCCOc4c3)c2n1

InChI Key: InChIKey=RSNMZPGHDNIUJO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50396944 (CHEMBL2170815) Show SMILES Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4OCCOc4c3)c2n1 Show InChI InChI=1S/C17H15N7O2/c1-23-10-12(7-19-23)13-8-18-16-17(20-13)24(22-21-16)9-11-2-3-14-15(6-11)26-5-4-25-14/h2-3,6-8,10H,4-5,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Competitive inhibition of N-terminal His6-tagged recombinant human c-MET (974 to 1390 amino acids) by spectrophotometry				J Med Chem 55: 8091-109 (2012) Article DOI: 10.1021/jm300967g BindingDB Entry DOI: 10.7270/Q2Z60Q59
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50396944 (CHEMBL2170815) Show SMILES Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4OCCOc4c3)c2n1 Show InChI InChI=1S/C17H15N7O2/c1-23-10-12(7-19-23)13-8-18-16-17(20-13)24(22-21-16)9-11-2-3-14-15(6-11)26-5-4-25-14/h2-3,6-8,10H,4-5,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at c-MET receptor in human A549 cells assessed as inhibition of autophosphorylation after 1 hr by ELISA				J Med Chem 55: 8091-109 (2012) Article DOI: 10.1021/jm300967g BindingDB Entry DOI: 10.7270/Q2Z60Q59
					More data for this Ligand-Target Pair