BDBM50397305 CHEMBL461360

SMILES: CNc1nc(nc2ccc(Cl)cc12)N1CC[C@H](N)C1

InChI Key: InChIKey=CMOWYBWYCJHODO-VIFPVBQESA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50397305 (CHEMBL461360) Show SMILES CNc1nc(nc2ccc(Cl)cc12)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C13H16ClN5/c1-16-12-10-6-8(14)2-3-11(10)17-13(18-12)19-5-4-9(15)7-19/h2-3,6,9H,4-5,7,15H2,1H3,(H,16,17,18)/t9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells				J Med Chem 51: 7855-65 (2008) Article DOI: 10.1021/jm800876b BindingDB Entry DOI: 10.7270/Q29Z964R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50397305 (CHEMBL461360) Show SMILES CNc1nc(nc2ccc(Cl)cc12)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C13H16ClN5/c1-16-12-10-6-8(14)2-3-11(10)17-13(18-12)19-5-4-9(15)7-19/h2-3,6,9H,4-5,7,15H2,1H3,(H,16,17,18)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]granisetron from 5HT3A receptor expressed in HEK293 cells after 24 hrs by scintillation counting in presence of quipazine				J Med Chem 55: 8603-14 (2012) Article DOI: 10.1021/jm300801u BindingDB Entry DOI: 10.7270/Q2RF5W5T
					More data for this Ligand-Target Pair