BDBM50397363 CHEMBL2170172

SMILES: Cc1cc(C)cc(COc2ccc(NC(=O)CCCCCCC(=O)OC(C)(C)C)cc2)c1

InChI Key: InChIKey=ULYOMFCVYIJWTP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50397363 (CHEMBL2170172) Show SMILES Cc1cc(C)cc(COc2ccc(NC(=O)CCCCCCC(=O)OC(C)(C)C)cc2)c1 Show InChI InChI=1S/C27H37NO4/c1-20-16-21(2)18-22(17-20)19-31-24-14-12-23(13-15-24)28-25(29)10-8-6-7-9-11-26(30)32-27(3,4)5/h12-18H,6-11,19H2,1-5H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...				Bioorg Med Chem Lett 22: 6621-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.104 BindingDB Entry DOI: 10.7270/Q2GX4CQR
					More data for this Ligand-Target Pair