null

SMILES: Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc(cc2)-c2nc(=O)o[nH]2)cc1Cl

InChI Key: InChIKey=QAXGZLPJWOSHHV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50397512 (CHEMBL2171025) Show SMILES Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc(cc2)-c2nc(=O)o[nH]2)cc1Cl Show InChI InChI=1S/C25H26Cl2N4O4/c26-21-6-5-20(15-22(21)27)34-19-9-13-30(14-10-19)18-7-11-31(12-8-18)24(32)17-3-1-16(2-4-17)23-28-25(33)35-29-23/h1-6,15,18-19H,7-14H2,(H,28,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human H1 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 22: 6688-93 (2012) Article DOI: 10.1016/j.bmcl.2012.08.124 BindingDB Entry DOI: 10.7270/Q2QF8V00
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50397512 (CHEMBL2171025) Show SMILES Clc1ccc(OC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc(cc2)-c2nc(=O)o[nH]2)cc1Cl Show InChI InChI=1S/C25H26Cl2N4O4/c26-21-6-5-20(15-22(21)27)34-19-9-13-30(14-10-19)18-7-11-31(12-8-18)24(32)17-3-1-16(2-4-17)23-28-25(33)35-29-23/h1-6,15,18-19H,7-14H2,(H,28,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to human CCR3 receptor expressed in CHOK1 cells by radioligand displacement assay				Bioorg Med Chem Lett 22: 6688-93 (2012) Article DOI: 10.1016/j.bmcl.2012.08.124 BindingDB Entry DOI: 10.7270/Q2QF8V00
					More data for this Ligand-Target Pair