null

SMILES: Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)c1ccccc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=HXFWRSDQHGMADM-VHZJUZHNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398763 (CHEMBL2179657) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)c1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C36H31ClN2O4/c37-27-11-8-22(9-12-27)26-16-25-18-36(43-34(41)23-4-2-1-3-5-23)29-17-24-10-13-28(40)32-30(24)35(36,33(42-32)31(25)38-19-26)14-15-39(29)20-21-6-7-21/h1-5,8-13,16,19,21,29,33,40H,6-7,14-15,17-18,20H2/t29-,33+,35+,36-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398763 (CHEMBL2179657) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)c1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C36H31ClN2O4/c37-27-11-8-22(9-12-27)26-16-25-18-36(43-34(41)23-4-2-1-3-5-23)29-17-24-10-13-28(40)32-30(24)35(36,33(42-32)31(25)38-19-26)14-15-39(29)20-21-6-7-21/h1-5,8-13,16,19,21,29,33,40H,6-7,14-15,17-18,20H2/t29-,33+,35+,36-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398763 (CHEMBL2179657) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)c1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C36H31ClN2O4/c37-27-11-8-22(9-12-27)26-16-25-18-36(43-34(41)23-4-2-1-3-5-23)29-17-24-10-13-28(40)32-30(24)35(36,33(42-32)31(25)38-19-26)14-15-39(29)20-21-6-7-21/h1-5,8-13,16,19,21,29,33,40H,6-7,14-15,17-18,20H2/t29-,33+,35+,36-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair