BDBM50398792 CHEMBL2177503
SMILES: C[C@@H](N1CCC(C1)c1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1
InChI Key: InChIKey=DXZBQYCXLSGSRO-LDCVWXEPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Phosphodiesterase 9A (Homo sapiens (Human)) | BDBM50398792 (CHEMBL2177503) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay | J Med Chem 55: 9055-68 (2012) Article DOI: 10.1021/jm3009635 BindingDB Entry DOI: 10.7270/Q2CR5VHK | |||||||||||
More data for this Ligand-Target Pair |