BDBM50398969 CHEMBL2179676

SMILES: Cn1cc2c(OCC3CCN(CCN4CCOCC4)CC3)nc3ccccc3c2c1

InChI Key: InChIKey=ZBBQTBSSMIXMQP-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50398969 (CHEMBL2179676) Show SMILES Cn1cc2c(OCC3CCN(CCN4CCOCC4)CC3)nc3ccccc3c2c1 Show InChI InChI=1S/C24H32N4O2/c1-26-16-21-20-4-2-3-5-23(20)25-24(22(21)17-26)30-18-19-6-8-27(9-7-19)10-11-28-12-14-29-15-13-28/h2-5,16-17,19H,6-15,18H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50398969 (CHEMBL2179676) Show SMILES Cn1cc2c(OCC3CCN(CCN4CCOCC4)CC3)nc3ccccc3c2c1 Show InChI InChI=1S/C24H32N4O2/c1-26-16-21-20-4-2-3-5-23(20)25-24(22(21)17-26)30-18-19-6-8-27(9-7-19)10-11-28-12-14-29-15-13-28/h2-5,16-17,19H,6-15,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2AR expressed in CHOK1 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50398969 (CHEMBL2179676) Show SMILES Cn1cc2c(OCC3CCN(CCN4CCOCC4)CC3)nc3ccccc3c2c1 Show InChI InChI=1S/C24H32N4O2/c1-26-16-21-20-4-2-3-5-23(20)25-24(22(21)17-26)30-18-19-6-8-27(9-7-19)10-11-28-12-14-29-15-13-28/h2-5,16-17,19H,6-15,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair