BDBM50399051 CHEMBL2178855

SMILES: Cc1cc(Oc2cccc(c2)C#N)nc(n1)-c1ccccc1

InChI Key: InChIKey=IWVUOCJAPYWQIA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (MIF) (Plasmodium falciparum)	BDBM50399051 (CHEMBL2178855) Show SMILES Cc1cc(Oc2cccc(c2)C#N)nc(n1)-c1ccccc1 Show InChI InChI=1S/C18H13N3O/c1-13-10-17(22-16-9-5-6-14(11-16)12-19)21-18(20-13)15-7-3-2-4-8-15/h2-11H,1H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...				J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7
					More data for this Ligand-Target Pair