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SMILES: COc1cc(C)cc(Oc2cc(C)nc(c2)N2CCOCC2)c1

InChI Key: InChIKey=MTVRVVKFPFPSMI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399056   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage migration inhibitory factor


(Plasmodium falciparum)		BDBM50399056
PNG
(CHEMBL2178849)
Show SMILES COc1cc(C)cc(Oc2cc(C)nc(c2)N2CCOCC2)c1
Show InChI InChI=1S/C18H22N2O3/c1-13-8-15(21-3)11-16(9-13)23-17-10-14(2)19-18(12-17)20-4-6-22-7-5-20/h8-12H,4-7H2,1-3H3
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PC cid
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UniChem

Similars
Article
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...

J Med Chem 55: 10148-59 (2012)


Article DOI: 10.1021/jm301269s
BindingDB Entry DOI: 10.7270/Q2FJ2HX7
More data for this
Ligand-Target Pair