BDBM50399191 CHEMBL2180157

SMILES: O=C(Nc1ccccc1OCCOc1ccccc1NC(=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=BWRJYFLQFYQEGV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 4 (Homo sapiens (Human))	BDBM50399191 (CHEMBL2180157) Show SMILES O=C(Nc1ccccc1OCCOc1ccccc1NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H24N2O4/c31-27(21-11-3-1-4-12-21)29-23-15-7-9-17-25(23)33-19-20-34-26-18-10-8-16-24(26)30-28(32)22-13-5-2-6-14-22/h1-18H,19-20H2,(H,29,31)(H,30,32)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincub...				J Med Chem 55: 9576-88 (2012) Article DOI: 10.1021/jm300845v BindingDB Entry DOI: 10.7270/Q2XK8GPN
					More data for this Ligand-Target Pair