BDBM50399549 CHEMBL2180895

SMILES: FC(F)(F)Oc1cccc(c1)C(=O)N1CCC(CC1)N(C1CC1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=XVGZUZGYIPSSIA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50399549 (CHEMBL2180895) Show SMILES FC(F)(F)Oc1cccc(c1)C(=O)N1CCC(CC1)N(C1CC1)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H22F6N2O4S/c24-22(25,26)16-4-2-6-20(14-16)36(33,34)31(17-7-8-17)18-9-11-30(12-10-18)21(32)15-3-1-5-19(13-15)35-23(27,28)29/h1-6,13-14,17-18H,7-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Cav2.2 expressed HEK293 cells assessed as inhibition of calcium flux by FLIPR assay in presence of 30 mM of potassium				J Med Chem 55: 9847-55 (2012) Article DOI: 10.1021/jm301056k BindingDB Entry DOI: 10.7270/Q26W9C7J
					More data for this Ligand-Target Pair