BDBM50399550 CHEMBL2180894
SMILES: FC(F)(F)Oc1ccccc1C(=O)N1CCC(CC1)N(C1CC1)S(=O)(=O)c1cccc(c1)C(F)(F)F
InChI Key: InChIKey=YNPRATQODWQQPG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human)) | BDBM50399550 (CHEMBL2180894) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of Cav2.2 expressed HEK293 cells assessed as inhibition of calcium flux by FLIPR assay in presence of 30 mM of potassium | J Med Chem 55: 9847-55 (2012) Article DOI: 10.1021/jm301056k BindingDB Entry DOI: 10.7270/Q26W9C7J | |||||||||||
More data for this Ligand-Target Pair |