null

SMILES: ONC(=O)c1cccc(c1)-c1cn(CCc2ccsc2)nn1

InChI Key: InChIKey=AIOBOFRJLHUCLQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50399673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50399673 (CHEMBL2178343) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccsc2)nn1 Show InChI InChI=1S/C15H14N4O2S/c20-15(17-21)13-3-1-2-12(8-13)14-9-19(18-16-14)6-4-11-5-7-22-10-11/h1-3,5,7-10,21H,4,6H2,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC6 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50399673 (CHEMBL2178343) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccsc2)nn1 Show InChI InChI=1S/C15H14N4O2S/c20-15(17-21)13-3-1-2-12(8-13)14-9-19(18-16-14)6-4-11-5-7-22-10-11/h1-3,5,7-10,21H,4,6H2,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC4 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50399673 (CHEMBL2178343) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccsc2)nn1 Show InChI InChI=1S/C15H14N4O2S/c20-15(17-21)13-3-1-2-12(8-13)14-9-19(18-16-14)6-4-11-5-7-22-10-11/h1-3,5,7-10,21H,4,6H2,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC1 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50399673 (CHEMBL2178343) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccsc2)nn1 Show InChI InChI=1S/C15H14N4O2S/c20-15(17-21)13-3-1-2-12(8-13)14-9-19(18-16-14)6-4-11-5-7-22-10-11/h1-3,5,7-10,21H,4,6H2,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC2 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50399673 (CHEMBL2178343) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccsc2)nn1 Show InChI InChI=1S/C15H14N4O2S/c20-15(17-21)13-3-1-2-12(8-13)14-9-19(18-16-14)6-4-11-5-7-22-10-11/h1-3,5,7-10,21H,4,6H2,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC8 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
					More data for this Ligand-Target Pair