BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

null

SMILES: ONC(=O)c1cccc(c1)-c1cn(CCc2ccccc2)nn1

InChI Key: InChIKey=HWLOIPFPGVBJBC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50399674
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50399674 (CHEMBL2178344) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccccc2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC6 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50399674 (CHEMBL2178344) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccccc2)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC4 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50399674 (CHEMBL2178344) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccccc2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC1 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50399674 (CHEMBL2178344) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccccc2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC2 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50399674 (CHEMBL2178344) Show SMILES ONC(=O)c1cccc(c1)-c1cn(CCc2ccccc2)nn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of HDAC8 by fluorometric assay				J Med Chem 55: 9562-75 (2012) Article DOI: 10.1021/jm300837y BindingDB Entry DOI: 10.7270/Q25X2B3Q
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair