BDBM50400332 CHEMBL2181521
SMILES: CC(C)Nc1cc(ncn1)-c1csc(n1)N(C)C(=O)c1ccc(Cl)cc1
InChI Key: InChIKey=RZWIAMDYZKVZRN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (RAT) | BDBM50400332 (CHEMBL2181521) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 22.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Radiological Sciences Curated by ChEMBL | Assay Description Displacement of [18F]FITM from mGlu1 receptor in rat brain homogenates after 1 hr by gamma counting | J Med Chem 55: 11042-51 (2012) Article DOI: 10.1021/jm301597s BindingDB Entry DOI: 10.7270/Q24Q7W5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (RAT) | BDBM50400332 (CHEMBL2181521) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Radiological Sciences Curated by ChEMBL | Assay Description Displacement of [18F]FITM from mGlu1 receptor in rat brain homogenates after 1 hr by gamma counting | J Med Chem 55: 11042-51 (2012) Article DOI: 10.1021/jm301597s BindingDB Entry DOI: 10.7270/Q24Q7W5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat)) | BDBM50400332 (CHEMBL2181521) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Radiological Sciences Curated by ChEMBL | Assay Description Displacement of [11C]-ABP688 from mGlu5 receptor in rat brain homogenates after 1 hr by gamma counting | J Med Chem 55: 11042-51 (2012) Article DOI: 10.1021/jm301597s BindingDB Entry DOI: 10.7270/Q24Q7W5R | |||||||||||
More data for this Ligand-Target Pair |