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BDBM50400418 CHEMBL2178454

SMILES: Cc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CCCC(O)=O)c(=O)oc12

InChI Key: InChIKey=YIMZKWNMSZEINE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400418   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400418
PNG
(CHEMBL2178454)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CCCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C28H26O5/c1-18-23-15-16-25(19(2)27(23)33-28(31)24(18)9-6-10-26(29)30)32-17-20-11-13-22(14-12-20)21-7-4-3-5-8-21/h3-5,7-8,11-16H,6,9-10,17H2,1-2H3,(H,29,30)
KEGG

UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair