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BDBM50400428 CHEMBL2178444

SMILES: Cc1c(OCc2ccc(cc2)-c2ccccc2C#N)ccc2c(C)c(CCC(O)=O)c(=O)oc12

InChI Key: InChIKey=ZYVRZXBHNDVDFA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400428   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400428
PNG
(CHEMBL2178444)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2C#N)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C28H23NO5/c1-17-22-11-13-25(18(2)27(22)34-28(32)23(17)12-14-26(30)31)33-16-19-7-9-20(10-8-19)24-6-4-3-5-21(24)15-29/h3-11,13H,12,14,16H2,1-2H3,(H,30,31)
KEGG

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair