BDBM50400430 CHEMBL2177811
SMILES: Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3ccc(cc3)-c3ccccc3)ccc12
InChI Key: InChIKey=DMVPDJZJSIIZFK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replicative DNA helicase (Bacillus anthracis) | BDBM50400430 (CHEMBL2177811) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Microbiotix Inc. Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay | J Med Chem 55: 10896-908 (2012) Article DOI: 10.1021/jm300922h BindingDB Entry DOI: 10.7270/Q2MS3TWV | |||||||||||
More data for this Ligand-Target Pair |