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BDBM50400438 CHEMBL2177803

SMILES: Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3ccc4ccc(Cl)cc4n3)ccc12

InChI Key: InChIKey=JGESENKRFIEGLJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400438   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400438
PNG
(CHEMBL2177803)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3ccc4ccc(Cl)cc4n3)ccc12
Show InChI InChI=1S/C23H18ClNO5/c1-13-18-7-6-17(11-21(18)30-23(28)19(13)8-9-22(26)27)29-12-16-5-3-14-2-4-15(24)10-20(14)25-16/h2-7,10-11H,8-9,12H2,1H3,(H,26,27)
KEGG

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair