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BDBM50400583 CHEMBL2206260

SMILES: CCCn1cnc2c(NC(c3ccccc3)c3ccccc3)nc(N[C@H](CC)CO)nc12

InChI Key: InChIKey=LECODPVGGAGDDA-HXUWFJFHSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400583   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-gated calcium channel subunit alpha Cav2.2


(Homo sapiens (Human))		BDBM50400583
PNG
(CHEMBL2206260)
Show SMILES CCCn1cnc2c(NC(c3ccccc3)c3ccccc3)nc(N[C@H](CC)CO)nc12 |r|
Show InChI InChI=1S/C25H30N6O/c1-3-15-31-17-26-22-23(29-25(30-24(22)31)27-20(4-2)16-32)28-21(18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,17,20-21,32H,3-4,15-16H2,1-2H3,(H2,27,28,29,30)/t20-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp method

ACS Med Chem Lett 3: 985-990 (2012)


Article DOI: 10.1021/ml3002083
BindingDB Entry DOI: 10.7270/Q2BC40P0
More data for this
Ligand-Target Pair