BDBM50400774 CHEMBL2204983

SMILES: CC1(CC1)OC(=O)N1CCC(CC1)n1ncc(COc2ccc(cc2)-n2cnnn2)c1C#N

InChI Key: InChIKey=SDGHYCIXEZKBLQ-UHFFFAOYSA-N

Data: 1 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50400774 (CHEMBL2204983) Show SMILES CC1(CC1)OC(=O)N1CCC(CC1)n1ncc(COc2ccc(cc2)-n2cnnn2)c1C#N Show InChI InChI=1S/C22H24N8O3/c1-22(8-9-22)33-21(31)28-10-6-18(7-11-28)30-20(12-23)16(13-25-30)14-32-19-4-2-17(3-5-19)29-15-24-26-27-29/h2-5,13,15,18H,6-11,14H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity to human GPR119				ACS Med Chem Lett 3: 955-958 (2012) Article DOI: 10.1021/ml300296q BindingDB Entry DOI: 10.7270/Q2SB46WV
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50400774 (CHEMBL2204983) Show SMILES CC1(CC1)OC(=O)N1CCC(CC1)n1ncc(COc2ccc(cc2)-n2cnnn2)c1C#N Show InChI InChI=1S/C22H24N8O3/c1-22(8-9-22)33-21(31)28-10-6-18(7-11-28)30-20(12-23)16(13-25-30)14-32-19-4-2-17(3-5-19)29-15-24-26-27-29/h2-5,13,15,18H,6-11,14H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at GPR119 in human HEK293 cells assessed as cAMP level by beta-lactamase reporter gene assay				ACS Med Chem Lett 3: 955-958 (2012) Article DOI: 10.1021/ml300296q BindingDB Entry DOI: 10.7270/Q2SB46WV
					More data for this Ligand-Target Pair
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50400774 (CHEMBL2204983) Show SMILES CC1(CC1)OC(=O)N1CCC(CC1)n1ncc(COc2ccc(cc2)-n2cnnn2)c1C#N Show InChI InChI=1S/C22H24N8O3/c1-22(8-9-22)33-21(31)28-10-6-18(7-11-28)30-20(12-23)16(13-25-30)14-32-19-4-2-17(3-5-19)29-15-24-26-27-29/h2-5,13,15,18H,6-11,14H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at GPR119 in human U20S cells assessed as binding to beta-arrestin by chemilumiscence analysis				ACS Med Chem Lett 3: 955-958 (2012) Article DOI: 10.1021/ml300296q BindingDB Entry DOI: 10.7270/Q2SB46WV
					More data for this Ligand-Target Pair