BDBM50401089 CHEMBL2204438

SMILES: COc1ccc(cc1)C#Cc1ccc(cc1)C(=O)N1CCC(C)(O)CC1

InChI Key: InChIKey=WFPGKHLTPZENGV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50401089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50401089 (CHEMBL2204438) Show SMILES COc1ccc(cc1)C#Cc1ccc(cc1)C(=O)N1CCC(C)(O)CC1 Show InChI InChI=1S/C22H23NO3/c1-22(25)13-15-23(16-14-22)21(24)19-9-5-17(6-10-19)3-4-18-7-11-20(26-2)12-8-18/h5-12,25H,13-16H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu3 assessed as thaillium flux through GIRK channels by cell-based assay				Bioorg Med Chem Lett 22: 3921-5 (2012) Article DOI: 10.1016/j.bmcl.2012.04.112 BindingDB Entry DOI: 10.7270/Q21N828X
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50401089 (CHEMBL2204438) Show SMILES COc1ccc(cc1)C#Cc1ccc(cc1)C(=O)N1CCC(C)(O)CC1 Show InChI InChI=1S/C22H23NO3/c1-22(25)13-15-23(16-14-22)21(24)19-9-5-17(6-10-19)3-4-18-7-11-20(26-2)12-8-18/h5-12,25H,13-16H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu3 assessed as thaillium flux through GIRK channels by cell-based assay				Bioorg Med Chem Lett 22: 3921-5 (2012) Article DOI: 10.1016/j.bmcl.2012.04.112 BindingDB Entry DOI: 10.7270/Q21N828X
					More data for this Ligand-Target Pair