null
SMILES: CC(C)(C(c1ccc(Nc2ccc(cc2)C(O)=O)cc1)n1cncn1)C(O)=O
InChI Key: InChIKey=JDLUQANAFAMTPT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50401160 (CHEMBL2205778) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA as substrate after 1 hr by scintillation counter analysis | Bioorg Med Chem 20: 4201-7 (2012) Article DOI: 10.1016/j.bmc.2012.05.076 BindingDB Entry DOI: 10.7270/Q2CZ3895 | |||||||||||
More data for this Ligand-Target Pair |