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SMILES: Cc1cc(CN2CCN(CC2)c2c(Cl)cnc3nc([nH]c23)-c2cc(C)on2)no1

InChI Key: InChIKey=HKDWDDUKCGQWFT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401420   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50401420
PNG
(CHEMBL2207510)
Show SMILES Cc1cc(CN2CCN(CC2)c2c(Cl)cnc3nc([nH]c23)-c2cc(C)on2)no1
Show InChI InChI=1S/C19H20ClN7O2/c1-11-7-13(24-28-11)10-26-3-5-27(6-4-26)17-14(20)9-21-19-16(17)22-18(23-19)15-8-12(2)29-25-15/h7-9H,3-6,10H2,1-2H3,(H,21,22,23)
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Similars
Article
PubMed
n/an/a 434n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to Aurora A kinase

J Med Chem 55: 8721-34 (2012)


Article DOI: 10.1021/jm300952s
BindingDB Entry DOI: 10.7270/Q22J6D2W
More data for this
Ligand-Target Pair