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SMILES: Cc1cc(CN2CCN(CC2)c2c(Cl)cnc3nc([nH]c23)-c2ccoc2)no1

InChI Key: InChIKey=QHGNCLOEPNSKIC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401427   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50401427
PNG
(CHEMBL2207508)
Show SMILES Cc1cc(CN2CCN(CC2)c2c(Cl)cnc3nc([nH]c23)-c2ccoc2)no1
Show InChI InChI=1S/C19H19ClN6O2/c1-12-8-14(24-28-12)10-25-3-5-26(6-4-25)17-15(20)9-21-19-16(17)22-18(23-19)13-2-7-27-11-13/h2,7-9,11H,3-6,10H2,1H3,(H,21,22,23)
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Similars
Article
PubMed
n/an/a 68n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to Aurora A kinase

J Med Chem 55: 8721-34 (2012)


Article DOI: 10.1021/jm300952s
BindingDB Entry DOI: 10.7270/Q22J6D2W
More data for this
Ligand-Target Pair