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BDBM50401452 CHEMBL2203800

SMILES: Cc1c(OCc2cccnc2)ccc2c1oc(=O)n(Cc1cccnc1)c2=O

InChI Key: InChIKey=BUEFNKRWVVXHRM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401452   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-dependent protein kinase


(Homo sapiens (Human))
BDBM50401452
PNG
(CHEMBL2203800)
Show SMILES Cc1c(OCc2cccnc2)ccc2c1oc(=O)n(Cc1cccnc1)c2=O
Show InChI InChI=1S/C21H17N3O4/c1-14-18(27-13-16-5-3-9-23-11-16)7-6-17-19(14)28-21(26)24(20(17)25)12-15-4-2-8-22-10-15/h2-11H,12-13H2,1H3
PDB

KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



La Trobe University

Curated by ChEMBL


Assay Description
Inhibition of DNA-PK using EPPLSQEAFADLWKK as substrate after 5 mins by ADP-Glo kinase assay


Eur J Med Chem 57: 85-101 (2012)


Article DOI: 10.1016/j.ejmech.2012.08.035
BindingDB Entry DOI: 10.7270/Q2XS5WK6
More data for this
Ligand-Target Pair