BDBM50401453 CHEMBL2203798

SMILES: Cc1c(OCc2cccnc2)ccc2c1oc(nc2=O)N(Cc1cccnc1)c1cccnc1

InChI Key: InChIKey=ZTASHDRXAZXCFT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50401453 (CHEMBL2203798) Show SMILES Cc1c(OCc2cccnc2)ccc2c1oc(nc2=O)N(Cc1cccnc1)c1cccnc1 Show InChI InChI=1S/C26H21N5O3/c1-18-23(33-17-20-6-3-11-28-14-20)9-8-22-24(18)34-26(30-25(22)32)31(21-7-4-12-29-15-21)16-19-5-2-10-27-13-19/h2-15H,16-17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of DNA-PK using EPPLSQEAFADLWKK as substrate after 5 mins by ADP-Glo kinase assay				Eur J Med Chem 57: 85-101 (2012) Article DOI: 10.1016/j.ejmech.2012.08.035 BindingDB Entry DOI: 10.7270/Q2XS5WK6
					More data for this Ligand-Target Pair