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SMILES: C[C@@H](Nc1c(Nc2ccccc2)c(=O)c1=O)C(C)(C)C

InChI Key: InChIKey=PBZCGYPOKVOUJC-SNVBAGLBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402067   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))		BDBM50402067
PNG
(CHEMBL2205467)
Show SMILES C[C@@H](Nc1c(Nc2ccccc2)c(=O)c1=O)C(C)(C)C |r|
Show InChI InChI=1S/C16H20N2O2/c1-10(16(2,3)4)17-12-13(15(20)14(12)19)18-11-8-6-5-7-9-11/h5-10,17-18H,1-4H3/t10-/m1/s1
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 3.20E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assay

Bioorg Med Chem Lett 22: 7615-22 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.009
BindingDB Entry DOI: 10.7270/Q2XK8GQ3
More data for this
Ligand-Target Pair