BDBM50402072 CHEMBL2206013

SMILES: Clc1ccc2NC(=O)\C(=C/c3ccc(OCCN4CCOCC4)cc3)c2c1

InChI Key: InChIKey=GYYJOGKYMRDFFT-UYRXBGFRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50402072 (CHEMBL2206013) Show SMILES Clc1ccc2NC(=O)\C(=C/c3ccc(OCCN4CCOCC4)cc3)c2c1 Show InChI InChI=1S/C21H21ClN2O3/c22-16-3-6-20-18(14-16)19(21(25)23-20)13-15-1-4-17(5-2-15)27-12-9-24-7-10-26-11-8-24/h1-6,13-14H,7-12H2,(H,23,25)/b19-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE method				Bioorg Med Chem Lett 22: 7634-40 (2012) Article DOI: 10.1016/j.bmcl.2012.10.016 BindingDB Entry DOI: 10.7270/Q2SX6FCN
					More data for this Ligand-Target Pair