BDBM50402073 CHEMBL2206008

SMILES: CCN(CC)CCOc1ccc(\C=C2/C(=O)Nc3ccc(Cl)cc23)cc1

InChI Key: InChIKey=LVFMFLDRHODBJZ-UYRXBGFRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50402073 (CHEMBL2206008) Show SMILES CCN(CC)CCOc1ccc(\C=C2/C(=O)Nc3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C21H23ClN2O2/c1-3-24(4-2)11-12-26-17-8-5-15(6-9-17)13-19-18-14-16(22)7-10-20(18)23-21(19)25/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,23,25)/b19-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE method				Bioorg Med Chem Lett 22: 7634-40 (2012) Article DOI: 10.1016/j.bmcl.2012.10.016 BindingDB Entry DOI: 10.7270/Q2SX6FCN
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