Found 4 hits for monomerid = 50402109 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50402109
(CHEMBL2207659)Show SMILES Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2cn[nH]c2C(F)(F)F)CC1 |r| Show InChI InChI=1S/C20H24ClF3N4O3/c1-12-8-13(21)2-3-17(12)31-15-4-6-28(7-5-15)11-14(29)9-25-19(30)16-10-26-27-18(16)20(22,23)24/h2-3,8,10,14-15,29H,4-7,9,11H2,1H3,(H,25,30)(H,26,27)/t14-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1... |
Bioorg Med Chem Lett 22: 7707-10 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.112
BindingDB Entry DOI: 10.7270/Q2JD4XZZ |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50402109
(CHEMBL2207659)Show SMILES Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2cn[nH]c2C(F)(F)F)CC1 |r| Show InChI InChI=1S/C20H24ClF3N4O3/c1-12-8-13(21)2-3-17(12)31-15-4-6-28(7-5-15)11-14(29)9-25-19(30)16-10-26-27-18(16)20(22,23)24/h2-3,8,10,14-15,29H,4-7,9,11H2,1H3,(H,25,30)(H,26,27)/t14-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Displacement of [3H]-pyrilamine from human recombinant H1 histamine receptor expressed in CHOK1 cells after 1 hr |
Bioorg Med Chem Lett 22: 7707-10 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.112
BindingDB Entry DOI: 10.7270/Q2JD4XZZ |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50402109
(CHEMBL2207659)Show SMILES Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2cn[nH]c2C(F)(F)F)CC1 |r| Show InChI InChI=1S/C20H24ClF3N4O3/c1-12-8-13(21)2-3-17(12)31-15-4-6-28(7-5-15)11-14(29)9-25-19(30)16-10-26-27-18(16)20(22,23)24/h2-3,8,10,14-15,29H,4-7,9,11H2,1H3,(H,25,30)(H,26,27)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in HEK cells by ion flux assay |
Bioorg Med Chem Lett 22: 7707-10 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.112
BindingDB Entry DOI: 10.7270/Q2JD4XZZ |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50402109
(CHEMBL2207659)Show SMILES Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2cn[nH]c2C(F)(F)F)CC1 |r| Show InChI InChI=1S/C20H24ClF3N4O3/c1-12-8-13(21)2-3-17(12)31-15-4-6-28(7-5-15)11-14(29)9-25-19(30)16-10-26-27-18(16)20(22,23)24/h2-3,8,10,14-15,29H,4-7,9,11H2,1H3,(H,25,30)(H,26,27)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Displacement of 3,7-Bis[2-(4-nitro[3,5]-[3H]phenyl)ethyl]-3,7-diazabicyclo[3.3.1]nonane from human ERG expressed in HEK cells after 3hrs |
Bioorg Med Chem Lett 22: 7707-10 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.112
BindingDB Entry DOI: 10.7270/Q2JD4XZZ |
More data for this
Ligand-Target Pair | |
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