BDBM50402129 CHEMBL2207669

SMILES: O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=PREVLKLSVWYCAY-QGZVFWFLSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50402129 (CHEMBL2207669) Show SMILES O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C25H25ClN4O4/c26-23-11-19(6-5-16(23)12-27)34-18-7-9-30(10-8-18)15-17(31)13-28-25(33)22-14-29-24(32)21-4-2-1-3-20(21)22/h1-6,11,14,17-18,31H,7-10,13,15H2,(H,28,33)(H,29,32)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4-(methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK1...				Bioorg Med Chem Lett 22: 7707-10 (2012) Article DOI: 10.1016/j.bmcl.2012.09.112 BindingDB Entry DOI: 10.7270/Q2JD4XZZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50402129 (CHEMBL2207669) Show SMILES O[C@H](CNC(=O)c1c[nH]c(=O)c2ccccc12)CN1CCC(CC1)Oc1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C25H25ClN4O4/c26-23-11-19(6-5-16(23)12-27)34-18-7-9-30(10-8-18)15-17(31)13-28-25(33)22-14-29-24(32)21-4-2-1-3-20(21)22/h1-6,11,14,17-18,31H,7-10,13,15H2,(H,28,33)(H,29,32)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-pyrilamine from human recombinant H1 histamine receptor expressed in CHOK1 cells after 1 hr				Bioorg Med Chem Lett 22: 7707-10 (2012) Article DOI: 10.1016/j.bmcl.2012.09.112 BindingDB Entry DOI: 10.7270/Q2JD4XZZ
					More data for this Ligand-Target Pair