BDBM50402210 CHEMBL2203972

SMILES: CCC#Cc1cc(-c2ccccc2)n(O)c(=O)c1

InChI Key: InChIKey=PTVPEMQIZODNAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glyoxalase 1 (GLO1) (Homo sapiens (Human))	BDBM50402210 (CHEMBL2203972) Show SMILES CCC#Cc1cc(-c2ccccc2)n(O)c(=O)c1 Show InChI InChI=1S/C15H13NO2/c1-2-3-7-12-10-14(16(18)15(17)11-12)13-8-5-4-6-9-13/h4-6,8-11,18H,2H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant GLO1 expressed in Escherichia coli BL21 assessed as decrease in reduced glutathione level after 1 hr by Ellman's meth...				Bioorg Med Chem Lett 22: 7486-9 (2012) Article DOI: 10.1016/j.bmcl.2012.10.045 BindingDB Entry DOI: 10.7270/Q2RX9D8Q
					More data for this Ligand-Target Pair