BDBM50402289 TENATOPRAZOLE
SMILES: COc1ccc2[nH]c(nc2n1)S(=O)Cc1ncc(C)c(OC)c1C
InChI Key: InChIKey=ZBFDAUIVDSSISP-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Indoleamine 2,3-dioxygenase 2 (Mus musculus) | BDBM50402289 (TENATOPRAZOLE) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom... | Bioorg Med Chem Lett 22: 7641-6 (2012) Article DOI: 10.1016/j.bmcl.2012.10.010 BindingDB Entry DOI: 10.7270/Q20G3M92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human)) | BDBM50402289 (TENATOPRAZOLE) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States. Curated by ChEMBL | Assay Description Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat... | Bioorg Med Chem Lett 27: 2962-2966 (2017) Article DOI: 10.1016/j.bmcl.2017.05.010 BindingDB Entry DOI: 10.7270/Q2W66P5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Mus musculus) | BDBM50402289 (TENATOPRAZOLE) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotom... | Bioorg Med Chem Lett 22: 7641-6 (2012) Article DOI: 10.1016/j.bmcl.2012.10.010 BindingDB Entry DOI: 10.7270/Q20G3M92 | |||||||||||
More data for this Ligand-Target Pair |