BDBM50402346 CHEMBL2206662

SMILES: O=C(Nc1ccccc1)Nc1cccc(Oc2ccc3nccn3n2)c1

InChI Key: InChIKey=DUACVOORSOOZRH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50402346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50402346 (CHEMBL2206662) Show SMILES O=C(Nc1ccccc1)Nc1cccc(Oc2ccc3nccn3n2)c1 Show InChI InChI=1S/C19H15N5O2/c25-19(21-14-5-2-1-3-6-14)22-15-7-4-8-16(13-15)26-18-10-9-17-20-11-12-24(17)23-18/h1-13H,(H2,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysis				Bioorg Med Chem 20: 7051-8 (2012) Article DOI: 10.1016/j.bmc.2012.10.004 BindingDB Entry DOI: 10.7270/Q2GF0VN9
					More data for this Ligand-Target Pair