null

SMILES: O[C@H](CNC(=O)c1cc(=O)[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=MAWNODXTLNGOAA-OAHLLOKOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50402822 (CHEMBL2208434) Show SMILES O[C@H](CNC(=O)c1cc(=O)[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C24H25Cl2N3O4/c25-20-6-5-17(11-21(20)26)33-16-7-9-29(10-8-16)14-15(30)13-27-24(32)19-12-23(31)28-22-4-2-1-3-18(19)22/h1-6,11-12,15-16,30H,7-10,13-14H2,(H,27,32)(H,28,31)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hr				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50402822 (CHEMBL2208434) Show SMILES O[C@H](CNC(=O)c1cc(=O)[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C24H25Cl2N3O4/c25-20-6-5-17(11-21(20)26)33-16-7-9-29(10-8-16)14-15(30)13-27-24(32)19-12-23(31)28-22-4-2-1-3-18(19)22/h1-6,11-12,15-16,30H,7-10,13-14H2,(H,27,32)(H,28,31)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50402822 (CHEMBL2208434) Show SMILES O[C@H](CNC(=O)c1cc(=O)[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C24H25Cl2N3O4/c25-20-6-5-17(11-21(20)26)33-16-7-9-29(10-8-16)14-15(30)13-27-24(32)19-12-23(31)28-22-4-2-1-3-18(19)22/h1-6,11-12,15-16,30H,7-10,13-14H2,(H,27,32)(H,28,31)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG in HEK cells by ion flux electrophysiology assay				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair