BDBM50403084 CHEMBL2216849

SMILES: CCNC(=O)Nc1nc2ccc(cc2s1)-c1cncc(c1)C(F)(F)F

InChI Key: InChIKey=WIYSJQLHHOXWOR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403084 (CHEMBL2216849) Show SMILES CCNC(=O)Nc1nc2ccc(cc2s1)-c1cncc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N4OS/c1-2-21-14(24)23-15-22-12-4-3-9(6-13(12)25-15)10-5-11(8-20-7-10)16(17,18)19/h3-8H,2H2,1H3,(H2,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair