BDBM50403091 CHEMBL2216872

SMILES: COc1ccc(NC(=O)c2c(C)oc3ncn(CC(C)C)c(=O)c23)cc1

InChI Key: InChIKey=XTZYDJFXBJTGSY-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50403091 (CHEMBL2216872) Show SMILES COc1ccc(NC(=O)c2c(C)oc3ncn(CC(C)C)c(=O)c23)cc1 Show InChI InChI=1S/C19H21N3O4/c1-11(2)9-22-10-20-18-16(19(22)24)15(12(3)26-18)17(23)21-13-5-7-14(25-4)8-6-13/h5-8,10-11H,9H2,1-4H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair