BDBM50403884 CHEMBL3142819::CHEMBL323339

SMILES: Cc1cn([C@H]2C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)n(CC(O)=O)c1=O

InChI Key: InChIKey=AXLGPTBFHIGEMJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50403884 (CHEMBL3142819 | CHEMBL323339) Show SMILES Cc1cn([C@H]2C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)n(CC(O)=O)c1=O |r| Show InChI InChI=1S/C24H44N2O7Si2/c1-16-13-25(22(30)26(21(16)29)14-20(27)28)19-12-17(33-35(10,11)24(5,6)7)18(32-19)15-31-34(8,9)23(2,3)4/h13,17-19H,12,14-15H2,1-11H3,(H,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Instituto de Química Médica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cells				Bioorg Med Chem Lett 11: 3085-8 (2001) BindingDB Entry DOI: 10.7270/Q2QC02S2
					More data for this Ligand-Target Pair