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SMILES: Cc1cn(C2CCC(CO[Si](C)(C)C(C)(C)C)O2)c(=O)n(CC(=O)OCc2ccccc2)c1=O

InChI Key: InChIKey=JIMNASJSRXLXKJ-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50403889   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50403889
PNG
(CHEMBL318807)
Show SMILES Cc1cn(C2CCC(CO[Si](C)(C)C(C)(C)C)O2)c(=O)n(CC(=O)OCc2ccccc2)c1=O
Show InChI InChI=1S/C25H36N2O6Si/c1-18-14-26(21-13-12-20(33-21)17-32-34(5,6)25(2,3)4)24(30)27(23(18)29)15-22(28)31-16-19-10-8-7-9-11-19/h7-11,14,20-21H,12-13,15-17H2,1-6H3
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MMDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a>2.50E+5n/an/an/an/a



Instituto de Química Médica (C.S.I.C.)

Curated by ChEMBL


Assay Description
Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cells

Bioorg Med Chem Lett 11: 3085-8 (2001)


BindingDB Entry DOI: 10.7270/Q2QC02S2
More data for this
Ligand-Target Pair